Cytokines and Liver Diseases
نویسندگان
چکیده
منابع مشابه
Interleukin-1 Family Cytokines in Liver Diseases
The gene encoding IL-1 was sequenced more than 30 years ago, and many related cytokines, such as IL-18, IL-33, IL-36, IL-37, IL-38, IL-1 receptor antagonist (IL-1Ra), and IL-36Ra, have since been identified. IL-1 is a potent proinflammatory cytokine and is involved in various inflammatory diseases. Other IL-1 family ligands are critical for the development of diverse diseases, including inflamm...
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Interest in cytokines in infection is increasing exponentially both because of the central role these peptide molecules have in immune responses in a wide spectrum of human responses in health and disease1 and because they are likely to be pivotal in the development of new therapies and vaccine strategies. Immunity to infections and attempts by pathogens to avoid the host defence system provide...
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The Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathway, activated by more than 50 cytokines or growth factors, plays critical roles in a wide variety of cellular functions in the hematopoietic, immune, neuronal and hepatic systems. In the liver, this signaling pathway, activated by more than 20 cytokines, growth factors, hormones, and hepatitis viral pr...
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Cytokines are small, secreted proteins that control immune responses. Within the lung, they can control host responses to injuries or infection, resulting in clearance of the insult, repair of lung tissue, and return to homeostasis. Problems can arise when this response is over exuberant and/or cytokine production becomes dysregulated. In such cases, chronic and repeated inflammatory reactions ...
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ژورنال
عنوان ژورنال: Canadian Journal of Gastroenterology
سال: 2001
ISSN: 0835-7900
DOI: 10.1155/2001/746736